UNRIVALLED SYNERGY™ OF 32 POTENT INGRDIENTS

Highlights by the numbers - daily amounts:

COP                                                                    1500 mg

Caffeine                                                                350 mg

Cissus quadrangularis - CQR-300®                  300 mg

Green Tea (98% polyphenols, 50% EGCG)       300 mg

Omega 3 (deep ocean fish source)                    200 mg

Citrus Aurantium - Advantra Z®                        100 mg

Biotin A water soluble B complex vitamin.  It plays a role in the metabolism of fatty acids and in gluconeogenesis.  Combined with chromium picolinate it has been shown to lower heart disease risk for type 2 diabetics.  It is also part of the citric acid cycle.  Helps the body to metabolize carbohydrates and proteins.  Daily recommended intake estimates range from 35 to 70 mcg per day.  Biotin is present in this formula at 0.225 mcg twice per day to provide 150% of RDA.

Folic acid (Vitamin B9) This is used in several body functions including DNA synthesis and repair.  Folic acid appears to reduce the risk of stroke.  Folate supplementation seems to help reduce blood pressure.  It is known as a heart healthy vitamin.  Folate is needed especially for cells that divide rapidly.  Helps to form red blood cells.  Helps the body metabolize proteins.  The recommended daily intake is 400 mcg per day for men and up to 800 mcg per day for women depending on age, etc.  Folic acid is present in this formula at 120 mcg twice per day to provide 60% of RDA because of female safety issues.

Magnesium Recommended for heart health and prevention of arrhythmias.  It helps prevent heart disease and diabetes.  Helps the body to metabolize carbohydrates, fats and proteins.  Helps in the development and maintenance of bones and teeth.  Helps in tissue formation.  Helps to maintain proper muscle function.  The recommended daily doses are 310 mg for women and 400 mg for men.  Magnesium is present in this formula at 100 mg twice a day to provide 50% of RDA.

Niacin (Vitamin B3) Niacin can help raise levels of HDL in the blood.  Helps the body to metabolize carbohydrates, fats and proteins.  Helps normal growth and development.  The effects on heart disease are still being studied.  It is known as a heart healthy vitamin.  The recommended daily intake is from 14 mg per day for women to 16 – 20 mg per day for men.  Niacin is present in this formula at 20 mg twice per day to provide 200% of RDA.

Pantothenic Acid (Vitamin B5) Low levels can affect the nervous system and may cause fatigue, parasthesias, muscle cramps etc. Decreased levels can also cause an increased sensitivity to insulin.  There are some studies that show pantothenic acid may help obese people lose weight.  Helps the body to metabolize carbohydrates, fats and proteins.  Helps in tissue formation.  The recommended daily intake is 10 mg per day. Pantothenic Acid is present in this formula at 7.5 mg twice per day to provide 150% of RDA.

Potassium Acts as a key body electrolyte. It helps lower blood pressure and is important for cardiac electrical activity.  The general body needs of potassium.  Potassium is heart healthy.  The recommended daily dose is up to 3500 mg a day from all sources.  Potassium is present in this formula at 32 mg twice per day to provide less than 1% of RDA.

Riboflavin (Vitamin B2) Has a key role to help the body metabolize carbohydrates, fats and proteins.  It is also known to help in red blood cell formation.  Thus, it is a heart healthy vitamin.  The recommended daily intake is 1.7 mg per day.  Riboflavin is present in this formula at 1.275 mg twice per day to provide 150% of RDA

Selenium Hypothesized to help prevent chronic heart disease.  Selenium concentrations were inversely correlated with cardiac disease in a large meta-analysis.  Thus, being heart healthy.  An antioxidant for maintenance of good health.  Recommended daily dose is 70 mcg.  Selenium is present in this formula at 52.5 mcg twice per day to provide 150% of RDA.

Thiamine (Vitamin B1) Helps convert carbohydrates into glucose.  Helps the body to metabolize carbohydrates, fats and proteins.  It has been called a heart healthy vitamin.  Helps normal growth.  Helps in the development of hair, nails, etc.  The recommended daily intake is up to 1.5 mg per day.  Thiamine is present in this formula at 1.25 mg twice per day to provide 160% of RDA.

Vitamin B6 A cofactor in many reactions of amino acid metabolism.  It also plays a role in gluconeogenesis.  It is a heart healthy vitamin helping the body to remove homocysteine.  Helps the body to metabolize carbohydrates, fats and proteins.  Helps in tissue formation.  The recommended daily intake is about 2 mg per day.  Vitamin B6 is present in this formula at 1.5 mg twice a day to provide 150% of RDA.

Vitamin B12 Has a key function in the brain and nervous system.  Helps the body to metabolize carbohydrates, fats and proteins.  Helps to form red blood cells.  It is a heart healthy vitamin.  The recommended daily intake is 2 to 3 mcg per day. Vitamin B12 is present in this formula at 4.5 mcg twice per day to provide 150% of RDA.

Vitamin C (Ascorbic Acid) Acts as an antioxidant and helps in oxidative stress.  Helps in the development and maintenance of bones, cartilage, teeth and gums.  Helps in would healing.  Helps in connective tissue formation.  Helps the body to metabolize carbohydrates, fats and proteins.  As an antioxidant it is called often a heart healthy vitamin.  Recommended daily intake is 60 mg per day.  Vitamin C is present in this formula at 45 mg twice per day to provide 150% of RDA.

Vitamin D3 (and D2) Helps in absorption and use of calcium and phosphorus.  Helps regulate blood pressure and inflammation and glucose levels.  (Heart health).  Various conditions such as depression and fatigue and even obesity are linked to low levels of vitamin D.  Daily intake recommended at 400 IU per day (400 mcg).  Helps in the maintenance of bones and teeth.  Vitamin D is present in this formula at 300 IU twice per day to provide 150% of the U.S. Recommended Dietary Allowance (RDA).

Vitamin K Useful in bone metabolism and blood coagulation.  It also helps to prevent intra-arterial calcification, thus helps prevent coronary artery disease.  Vitamin K2 is heart healthy.  Helps in the maintenance of bones.  The recommended daily intake is from 80 mcg a day.  Vitamin K2 is present in this formula at 60 mcg twice per to provide 150% of RDA.

Zinc Deficiency can indicate increase risk of cardiac problems due to increased inflammatory mediators.  It can help maintain the immune system.  Zinc is heart healthy.  Helps with the maintenance of skin, nails and hair.  Helps in connective tissue formation.  Helps the body to metabolize carbohydrates, fats and proteins. Recommended daily dose is 15 mg.  Zinc is present in this formula at 11.25 mg twice per day to provide 150% of RDA. 

Betaine Also known as Trimethyl Glycine.  Acts as a methyl donor to help maintain health.  Betaine is considered heart healthy since it lowers homocysteine levels.   Also used in joint building. 

Bitter Orange (Advantra Z® 6%) Also known as citrus aurantium.  Bitter orange refers to a citrus tree and its fruit.  It has been used in herbal preparations for hundreds of years.  A form of p-synephrine also known as octopamine.  These are similar to medical synephrine except p-synephrine does not have the cardiac activity.  P-synephrine 6% has been shown in several clinical studies to assist in facilitating weight loss in combination with a proper diet and exercise program.  It has also been shown to increase thermic effect in patients.     

Caffeine Anhydrous Helps (temporarily) to relieve fatigue, to promote endurance, and to enhance motor performance.  Helps (temporarily) to promote alertness and wakefulness, and to enhance cognitive performance.  Can be used temporarily as a mild diuretic. 

Cissus quadrangularis CQR-300® Also known as Veldt-grape, plant member of the grape family.  It is native to India and also found in South Africa. It has been used as a medicinal plant for hundreds of years.  Helps decrease appetite and facilitate weight loss in conjunction with a proper diet and exercise program.  Helps burn cholesterol for energy and through the glut 4 mechanism, pushes sugar from the blood into muscle cells.  Through this action, the body senses low blood sugar and regulates the insulin level.  Insulin decreases appetite and helps metabolize the sugar and provide energy as well as increasing alertness.  Three double blind placebo controlled clinical trials have consistently maintained efficacy as a weight loss assistant agent with proper diet and exercise.  Cissus has known serotonin like effects which can affect the appetite centers of the brain.  Cissus is also known to help decrease blood glucose and to improve serum lipid profiles in clinical studies.  Cissus also has positive bone mineralization effects.   Cissus has also shown to be heart healthy.   

Coenzyme Q10 Also known as ubiquinone.  Coenzyme Q10 helps to maintain and or support cardiovascular health.  Thus, known as heart healthy.  Helps to reduce the frequency of migraine headaches and associated nausea and vomiting when taken as a prophylactic.  Used as an antioxidant in the maintenance of good health. 

Corosolic Acid Also known as 2-alpha-Hydroxyirosolic acid.  This is plant derived from Lagerstroemia speciosa which helps to maintain normal blood glucose levels.  Thus, being heart healthy. 

Creatinol-o-phosphate (COP) Creatinaol-o-phosphate IS NOT CREATINE!  COP has a completely different molecular weight and CAS (Chemical Identification Number).  COP has far different actions in the body than creatine.  COP helps to stabilize the pH or acidity level in and out of the cells.  This facilitates muscle contractions and mitochondrial functions to continue further allowing athletes to perform more intensely and train longer.   Thus, helps build bigger, leaner muscles.

Dandelion Powder Also known as taraxacum officinale comes from dandelion leaf.  Dandelion powder contains a number of biologically active compounds such as terpines, sterols, polysaccharides etc.  Dandelion has been used as an herbal diuretic.  

Geranium Robertonium Used as powdered dried leaves.  Geranium powder WITHOUT DMAA is ground geranium plant material. Geranium can be used as an astringent and sometimes antiseptic.  It has been known to help mental alertness.  Geranium can increase peripheral circulation.  It also seems to enhance the oxygen availability at the cell level.  Geranium may also enhance the immune system and is a mild diuretic. It is also felt to help reduce free radicals in the blood. 

Grape Seed Powder (Resveratrol) Used as an antioxidant for maintenance of good health.  Also helps to relieve symptoms of non-complicated chronic venous insufficiency (CVI), such as sensation of swelling, heaviness of “cold” feet or hands.  Resveratrol may help reduce inflammation and inflammatory response after heavy bouts of training and exercise.  This is known as heart healthy. 

Green Tea Extract (98% phenols and 50% EGCG) Helps facilitate weight loss by increasing energy expenditure and fat oxidation in conjunction with a proper diet and exercise program.  Proven in clinical trials to assist in calorie burning resulting in possible weight loss.  Clinically proven to be thermogenic.  Green tea has also shown to help strengthen the lining of small blood vessels.  Thus, this is considered heart healthy.  In addition, serves as an antioxidant for the maintenance of good health.  Green tea is also mildly diuretic.

Notoginseng /Panax Ginseng An herbal root used as supportive therapy for the promotion of healthy blood glucose levels.  Helps support cognitive function and or reduce mental fatigue.  Also helps enhance physical capacity / performance in cases of physical stress.

Omega - 3 Concentrate Omega – 3 in this formula is Eicosapentanoic Acid (EPA) and Docosapentanoic Acid (DHA) from fish body oil.  It helps to maintain and support cardiovascular and health.  Thus, Omega – 3 is heart healthy.  It also helps to support cognitive health and or brain function.

Pine Bark Extract An antioxidant used for the support and maintenance of overall good health.  Pine bark also has some slight salyclate (aspirin) effects and may help improve blood flow, especially in small vessels.  Thus, being heart healthy.   Pine bark extract is present in this formula at 30 mg per day. 

Piperine Derived from the plant material piper nigrum.  Piperine helps to enhance the biologic activities of other compounds.  It is used in this formulation since it can help boost the bioavailability of the grape seed extract (resveratrol) component.  Thus, being heart healthy.  The piperine can also boost the bioavailability of other key ingredients. 

R-alpha-Lipoic Acid Also known as pentanoic acid, is known as an excellent antioxidant.  It has been known to help in wound healing as well as having Vitamin B like activity.  ALA is known to be heart healthy.  It may also help in glucose metabolism.   

Yohimbe Bark Extract Yohimbe is an alkaloid which is found naturally in the bark of pausinystalia yohimbe plant among other sources.  By blocking alpha 2 receptors it helps relax smooth muscles of the body.  One of the effects is vasodilation.   Vasodilation can increase blood flow to the muscles in intense exercise.  It can also increase skin temperature and possibly thermogenesis.  One study showed fat loss in athletes.  It helps increase awareness and may help concentration and focus.